The output shelf, dialed for protocols.
Two compounds drive the performance research conversation: Ipamorelin/CJC-1295 for pulsatile growth hormone work, and MOTS-c for mitochondrial peptide research. Different mechanisms, both targeting body composition and exercise-capacity endpoints.
Ipa/CJC Blend
Ipamorelin (selective ghrelin agonist) + CJC-1295 (long-acting GHRH analog). The canonical GH-pulse research blend.
MOTS-c 10 mg
Mitochondrial peptide acting upstream of AMPK. Metabolic flexibility, exercise capacity, mitochondrial biogenesis research.
Two signals, two very different mechanisms.
Performance research splits cleanly along mechanism. One axis is pulsatile growth hormone — what your pituitary releases at night, what GHRH analogs amplify, what GH-secretagogues like the ipamorelin family modulate. The other is mitochondrial — the cell's ability to produce ATP under load.
Ipamorelin paired with CJC-1295 is the canonical GH-pulse research stack. Ipamorelin is a selective ghrelin receptor agonist that triggers a clean GH pulse; CJC-1295 is a long-acting GHRH analog that sustains the pulse. Together they produce the most reproducible GH curve in the research literature, with minimal cortisol or prolactin off-target.
MOTS-c is a 16-amino mitochondrial-derived peptide identified in 2015. It operates upstream of AMPK — it doesn't signal at the cell surface like the GH stack does — and the research is dense on metabolic flexibility, exercise capacity, and mitochondrial biogenesis endpoints.
Below: the two products, the stacks patients run alongside, and a decision tree if you're deciding between mechanisms.
Three questions, one starting molecule.
Studying body composition?
GH-axis modulation has the longest performance-research record for lean-mass, body-composition, and recovery-adjacent endpoints. The Ipa/CJC blend is the cleanest entry point.
Pick → Ipa / CJC
Studying exercise capacity?
MOTS-c's mitochondrial mechanism makes it the right molecule when the research endpoint is VO2, work-rate output, or metabolic flexibility under load. Different conversation from GH. · Pick
Pick → MOTS-c
Both, in one protocol?
They don't compete for receptors and have meaningfully different half-lives, which makes them stackable. Several published protocols combine them — see the stacks below for the canonical pairing.
Pick → Both, stacked
Stacks patients run alongside.
All 9 stacks →
Patient questions, answered.
Six things we get asked most about the performance lane. For dosing math, use the calculator. For purity records, every PDP has the full COA archive.
Why pair Ipamorelin with CJC-1295?
They cover two different ends of the GH pulse. Ipamorelin triggers the pulse via the ghrelin receptor; CJC-1295's GHRH analog activity sustains it. Run separately, the curve is short and small. Run together, it's longer and more reproducible.
Is the Ipa/CJC blend the DAC version or non-DAC?
We supply the non-DAC version of CJC-1295 in the blend. DAC has a longer terminal half-life but produces a less-defined pulse. Most published protocols use non-DAC for cleaner pharmacokinetics.
When in the day are these typically administered in research?
GH-pulse research protocols typically dose at night to mimic endogenous pulse timing. MOTS-c protocols vary; the literature has both peri-exercise and chronic schedules.
Does MOTS-c require cold shipping?
Lyophilized MOTS-c ships room-temp safely for ≤72h, which we exceed comfortably with USA overnight. Reconstituted material should be refrigerated and used within window per literature.
Can I use the Ipa/CJC blend long-term in a research protocol?
Most published protocols use 3-months-on / 1-month-off cycling to avoid receptor desensitization. We don't make recommendations — see your study design.
What's the COA cadence on this lane?
Every lot, no exceptions. ISO-17025 third-party HPLC + mass spec, plus endotoxin, plus residual solvents. Each PDP shows the lot number you'll receive and links to the matching COA.
Run the canonical GH stack?
Ipa/CJC + BPC-157 is the most-ordered performance combination. Pre-bundled, pre-saved, with the full COA chain attached.